NanoSiliCal Devices is a spin-off at the University of Calabria, founded in 2014 by the research team made up by Prof. Luigi Pasqua, Prof. Antonella Leggio and Dr. Catia Morelli. It aims to develop nanostructured products that may be exploited as smart anticancer therapies, basing its activities on the results of experimental studies, gained in the last 10 years, that haveled to several International Patent Applications and publications on international journals with high impact factor. Research and development activities are the aim of the innovative nature of NanoSiliCal Devices.
NanoSiliCal Devices produces multi-functional nano-structured systems, based on mesoporous silica (Mesoporous Silica Nanoparticles, MSNs), for the intracellular release of biologically active molecules. MSNs are highly versatile systems, since different kinds of organic ligands can be grafted on the MSNs surface to provide hybrid and multifunctional solutions of high therapeutic interest, which are able to target specific tissues, e.g by selectively directing a drug to cancer cells.
NanoSiliCal Devices is the result of several studies based on properties, synthesis, characterization and biological validation of mesoporous silicas.These studies involve a modular method of synthesis of mesoporous silica based micro-and nano-systems that could be used for drug delivery. Mesoporous silica nanodevices (MSN) bearing a targeting molecule on the outer surface and a specific drug linked within the pores, as vehicles for targeting and release of biologically active molecules, are developed to be employed in targeted therapy. This is an excellent drug delivery system based on Receptor-specific ligand on the external surface and drug inside the pores.
Our Mission
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Our Vision
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Our TeamWho’s behind the scenes?
ProfessionalVivamus Ultricies Fermentum
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PerfectionCurabitur Cursus Pretium
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QualityNunc Purus Tellus
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MilestonesBrief History of Our Company
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